Hyaluronic acid (HA) is a naturally occurring polysaccharide that gives structure to tissues and contributes to the optimal functioning of a number of biological systems in the human
body . Because of its intrinsic biocompatibility, biodegradability, and diverse biological functions, HA is widely used in medical devices and pharmaceutical applications, for example eye
drops, viscoelastic devices, and topical formulations. HA also adds new and improved attributes to existing products, while also offering numerous opportunities when developing new ones.
HA for Skin Care Applications
Dermatology is a unique medical specialty dealing with the skin and its diseases. It includes both medical and clinical aspects in the widest sense and addresses issues of the skin, scalp, hair, and nails.
Hyaluronic acid (HA) has distinguished itself in the cosmetic industry due to its incomparable moisturizing properties. Indeed, HA is one of the most hygroscopic molecules found in nature, a property which confers its ability to attract and retain moisture from its immediate environment & later, the documented ability of HA to scavenge reactive oxygen species (free radicals) in vitro earned this naturally occurring macromolecule, the status of being one of the most preferred anti-aging agents for cosmetic products.
As a major component of the skin, hyaluronic acid supports epidermal barrier function and is considered to be the most active guardian of the extracellular matrix homeostasis.
Keys Benefits for Cosmetic Applicationeys
· Moisturizing
· Film Forming
· Anti – Aging
· Healing
· Skin Rejuvenation
· Nutrition Delivery
· Radical Scavenging
· Combat inflammatory conditions
General Specification of Sodium Hyaluronate (Cosmetic Grade) |
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Working Parameters |
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High / Medium Molecular Weight |
Low Molecular Weight |
HA - Oligo |
HA,1% Aqueous Solution |
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Fermentation Culture Method |
Streptococcus Zooepidemicus |
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Appearance |
White, Fine Powder |
White, Fine Powder |
White, Fine Powder |
Clear Viscous Liquid |
pH |
6.0 - 7.5 |
6.0 - 7.5 |
3.0 - 5.0 |
6.0 - 7.5 |
Transparency |
≥99.0% |
≥99.0% |
≥99.0% |
≥97.0% |
Loss on drying |
≤10.0% |
≤10.0% |
≤10.0% |
N.A |
Molecular weight |
(1.00 - 3.00) x 10⁶ |
(0.01 - 1.00) x 10⁶ |
≤0.01 x 10⁶ |
(1.3 - 1.6) x 10⁶ |
Protein |
≤0.05% |
≤0.05% |
≤0.1% |
≤0.002% |
Heavy metals |
≤20 ppm |
≤20 ppm |
≤20 ppm |
≤20 ppm |
Glucuronic acid |
≥44.0% |
≥44.0% |
≥44.0% |
≥4.5 mg/ml |
Sodium hyaluronate |
≥91.0% |
≥91.0% |
≥91.0% |
1% |
Microbial Limit Test |
<100 cfu/g |
<100 cfu/g |
<100 cfu/g |
<100 cfu/g |
Mold & Yeast counts |
<10 cfu/g |
<10 cfu/g |
<10 cfu/g |
<10 cfu/g |
Staphylococcus Aureus |
Negative |
Negative |
Negative |
Negative |
Pseudomonas Aeruginosa |
Negative |
Negative |
Negative |
Negative |
Packaging |
100g & 1kg |
100g & 1kg |
100g & 1kg |
1kg & 20KG |
Storage Conditions |
Stored in Sealed Container in dark place at 2-8 degrees celsius |
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Expiration Date |
3 years from manufacture date |
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Displayed Name (INCI Code) |
Sodium Hyaluronate |
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CAS No. |
9067-32-7 |
產品編號與說明
產品名 | 分子量 | INCI Name | 使用量 |
HAC200 | 180~200萬 | Sodium Hyaluronate | 0.01% - 0.3% |
HAC150 | 100~150萬 | Sodium Hyaluronate | 1% |
HAC050 | 20~50萬 | Sodium Hyaluronate | 0.05% –0.2% |
HAC020 | 1~20萬 | Sodium Hyaluronate | 0.1% - 0.5% |
HAC001 | 1萬以下 | Sodium Hyaluronate | 0.1% - 0.5% |