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Cosmetic Ingredients>Hyaluronic acid

HA

Product Information

Hyaluronic acid (HA) is a naturally occurring polysaccharide that gives structure to tissues and contributes to the optimal functioning of a number of biological systems in the human body. Because of its intrinsic biocompatibility, biodegradability, and diverse biological functions, HA is widely used in medical devices and pharmaceutical applications, for example eye drops, viscoelastic devices, and topical formulations. HA also adds new and improved attributes to existing products, while also offering numerous opportunities when developing new ones.

 

HA for Skin Care Applications

Dermatology is a unique medical specialty dealing with the skin and its diseases. It includes both medical and clinical aspects in the widest sense and addresses issues of the skin, scalp, hair, and nails.

Hyaluronic acid (HA) has distinguished itself in the cosmetic industry due to its incomparable moisturizing properties. Indeed, HA is one of the most hygroscopic molecules found in nature, a property which confers its ability to attract and retain moisture from its immediate environment & later, the documented ability of HA to scavenge reactive oxygen species (free radicals) in vitro earned this naturally occurring macromolecule, the status of being one of the most preferred anti-aging agents for cosmetic products.

As a major component of the skin, hyaluronic acid supports epidermal barrier function and is considered to be the most active guardian of the extracellular matrix homeostasis.

 

Key Benefits for Cosmetic Application

·         Moisturizing

·         Film Forming

·         Anti – Aging

·         Healing

·         Skin Rejuvenation

·         Nutrition Delivery

·         Radical Scavenging

·         Combat inflammatory conditions 

 

 

 General Specification of Sodium Hyaluronate (Cosmetic Grade)
         
 

Working Parameters
 

High / Medium Molecular Weight

Low Molecular Weight

HA - Oligo

HA,1% Aqueous Solution

Fermentation Culture Method

Streptococcus Zooepidemicus

Appearance

White, Fine Powder

White, Fine Powder

White, Fine Powder

Clear Viscous Liquid

pH

6.0 - 7.5

6.0 - 7.5

3.0 - 5.0

6.0 - 7.5

Transparency

≥99.0%

≥99.0%

≥99.0%

≥97.0%

Loss on drying

≤10.0%

≤10.0%

≤10.0%

N.A

Molecular weight

(1.00 - 3.00) x 10⁶

(0.01 - 1.00) x 10⁶

≤0.01 x 10⁶

(1.3 - 1.6) x 10⁶

Protein

≤0.05%

≤0.05%

≤0.1%

≤0.002%

Heavy metals

≤20 ppm

≤20 ppm

≤20 ppm

≤20 ppm

Glucuronic acid

≥44.0%

≥44.0%

≥44.0%

≥4.5 mg/ml

Sodium hyaluronate

≥91.0%

≥91.0%

≥91.0%

1%

Microbial Limit Test

<100 cfu/g

<100 cfu/g

<100 cfu/g

<100 cfu/g

Mold & Yeast counts

<10 cfu/g

<10 cfu/g

<10 cfu/g

<10 cfu/g

Staphylococcus Aureus

Negative

Negative

Negative

Negative

Pseudomonas Aeruginosa

Negative

Negative

Negative

Negative
         

Packaging

100g & 1kg

100g & 1kg

100g & 1kg

1kg & 20KG

Storage Conditions

Stored in Sealed Container in dark place at 2-8 degrees celsius

Expiration Date

3 years from manufacture date

Displayed Name (INCI Code)

Sodium Hyaluronate

CAS No.

9067-32-7

 

Product Description

Product Code 

Molecular weight

 INCI Name Dosage
HAC200 1.8 - 2 Mda Sodium Hyaluronate 0.01% - 0.3%
HAC150 1-1.5 Mda Sodium Hyaluronate 1%
HAC050 200 - 500 Kda Sodium Hyaluronate 0.05% - 0.2%
HAC020 10 - 200 Kda Sodium Hyaluronate 0.1% - 0.5%
HAC001 ≤ 10 Kda Sodium Hyaluronate 0.1% - 0.5%

 

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